{"id":1893,"date":"2021-10-05T12:00:27","date_gmt":"2021-10-05T04:00:27","guid":{"rendered":"https:\/\/365cps.org.sg\/resourcehub\/?p=1893"},"modified":"2023-01-31T10:44:37","modified_gmt":"2023-01-31T02:44:37","slug":"personalised-treatment-to-fight-lung-cancer","status":"publish","type":"post","link":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/","title":{"rendered":"Personalised Treatment to Fight Lung Cancer"},"content":{"rendered":"

Heavy smokers, typically men, run a high risk of developing lung cancer due to the carcinogenic compounds found in tobacco smoke.<\/p>\n

But while tobacco remains the main risk factor, there has been a rising number of female lung cancer patients who have never smoked \u2014 with recognition that treatment for lung cancer in non-smokers can be different.<\/p>\n

There are certain genetic mutations that can lead to lung cancer that is more commonly found in Asian female non-smokers, according to Dr Tan Chee Seng, senior medical oncologist at OncoCare Cancer Centre, Singapore.<\/p>\n

\u201cLung cancer is unique in Asia. A mutation in the epidermal growth factor receptor (EGFR) may account for up to 50 per cent of female lung cancer cases here. But for Caucasians, it is less than 10 per cent due to genetic differences,\u201d Dr Tan added.<\/p>\n

Chemotherapy \u2014 Not The Only Solution, Role Of Oral Targeted Therapy<\/b><\/p>\n

Thanks to new forms of treatment options recently developed, those suffering from advanced stage lung cancer now can have access to more personalised treatment options.\u00a0Increasingly these newer treatment options are getting approval to be used to treat early lung cancers.<\/p>\n

Dr Tan also advised patients to undergo several genetic\/molecular tests to determine the cause of their cancer, as certain types of genetic mutations can be treated with targeted therapy drugs or immunotherapy.<\/p>\n

Advancements in technology have made it possible to consider \u2018liquid\u2019 biopsy for selected patients where routine biopsies are not viable. These are essentially routine blood tests but with some limitations like lower accuracy (sensitivity\/specificity). Also, not all genetic mutations can be tested through this method.<\/p>\n

Lung cancer patients who test positive for the EGFR mutation have the option to take tyrosine kinase inhibitor (TKI), a type of oral drug, as the first line of treatment. Unlike chemotherapy, which affects all body cells, TKI mainly inhibits the growth and spread of cancer cells. Common side effects include diarrhoea and face pimples.<\/p>\n

At the present moment, there are three generations of EGFR TKI drugs developed to fight lung cancer.<\/p>\n

The latest third generation EGFR TKI has the added benefit of treating brain metastases and has also significantly reduced common side effects. Singapore is one of the first few countries in the region to have access to this medication, noted Dr Tan.<\/p>\n

Immunotherapy<\/strong><\/p>\n

However, not all lung cancer patients can be targeted by TKI. Alternative treatment options include chemotherapy with or without the addition of immunotherapy\/biologics.<\/p>\n

In selected patients, it is possible to use immunotherapy alone as the frontline treatment. Immunotherapy is a new class of lung cancer treatment that stimulates patient\u2019s own immune system to fight cancer cells and has been shown to have lower side effects compared to conventional chemotherapy.<\/p>\n

 <\/p>\n

For more information, please visit the following link: Lung Cancer Treatment And Diagnosis<\/a><\/em><\/p>\n

This article is contributed by Dr Tan Chee Seng, Senior Medical Oncologist at\u00a0OncoCare Cancer Centre<\/a>.\u00a0<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Heavy smokers, typically men, run a high risk of developing lung cancer due to the carcinogenic compounds found in tobacco smoke. But while tobacco remains the main risk factor, there…<\/p>\n","protected":false},"author":3,"featured_media":1894,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[74,6,9],"tags":[53,68],"class_list":{"0":"post-1893","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-blogs","8":"category-education","9":"category-cancer-info","10":"tag-cancer","11":"tag-cancer-treatment"},"acf":{"standfirst":"Heavy smokers, typically men, run a high risk of developing lung cancer due to the carcinogenic compounds found in tobacco smoke.","author_":"Dr Tan Chee Seng","job_title":"Senior Medical Oncologist","organisation":"OncoCare Cancer Centre","link":"","post_header_image":1894,"background_alignment":"center"},"yoast_head":"\nPersonalised Treatment to Fight Lung Cancer | 365 Cancer Prevention Society<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Personalised Treatment to Fight Lung Cancer | 365 Cancer Prevention Society\" \/>\n<meta property=\"og:description\" content=\"Heavy smokers, typically men, run a high risk of developing lung cancer due to the carcinogenic compounds found in tobacco smoke. But while tobacco remains the main risk factor, there...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"365 CPS Resource Hub\" \/>\n<meta property=\"article:published_time\" content=\"2021-10-05T04:00:27+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-01-31T02:44:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Lim\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lim\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/\"},\"author\":{\"name\":\"Lim\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/person\/6afe96e22e1780f4859a3cab24192bd3\"},\"headline\":\"Personalised Treatment to Fight Lung Cancer\",\"datePublished\":\"2021-10-05T04:00:27+00:00\",\"dateModified\":\"2023-01-31T02:44:37+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/\"},\"wordCount\":486,\"publisher\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#organization\"},\"image\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg\",\"keywords\":[\"Cancer\",\"Cancer Treatment\"],\"articleSection\":[\"Blogs\",\"Cancer Education\",\"Cancer Info\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/\",\"url\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/\",\"name\":\"Personalised Treatment to Fight Lung Cancer | 365 Cancer Prevention Society\",\"isPartOf\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg\",\"datePublished\":\"2021-10-05T04:00:27+00:00\",\"dateModified\":\"2023-01-31T02:44:37+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#primaryimage\",\"url\":\"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg\",\"contentUrl\":\"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg\",\"width\":2560,\"height\":1707},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Resources\",\"item\":\"https:\/\/365cps.org.sg\/resourcehub\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cancer Education\",\"item\":\"https:\/\/365cps.org.sg\/resourcehub\/category\/education\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Personalised Treatment to Fight Lung Cancer\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#website\",\"url\":\"https:\/\/365cps.org.sg\/resourcehub\/\",\"name\":\"365 CPS Resource Hub\",\"description\":\"Your ultimate cancer resource\",\"publisher\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/365cps.org.sg\/resourcehub\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#organization\",\"name\":\"365 CPS Resource Hub\",\"url\":\"https:\/\/365cps.org.sg\/resourcehub\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/10\/365CPS-Logo-Retina.webp\",\"contentUrl\":\"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/10\/365CPS-Logo-Retina.webp\",\"width\":240,\"height\":175,\"caption\":\"365 CPS Resource Hub\"},\"image\":{\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/person\/6afe96e22e1780f4859a3cab24192bd3\",\"name\":\"Lim\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/cf6824ffefdf977dbbdf99efe33156c5dd8c50b6dd7e48e456248983f497d62c?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/cf6824ffefdf977dbbdf99efe33156c5dd8c50b6dd7e48e456248983f497d62c?s=96&d=mm&r=g\",\"caption\":\"Lim\"},\"url\":\"https:\/\/365cps.org.sg\/resourcehub\/author\/yunqianlim\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Personalised Treatment to Fight Lung Cancer | 365 Cancer Prevention Society","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/","og_locale":"en_US","og_type":"article","og_title":"Personalised Treatment to Fight Lung Cancer | 365 Cancer Prevention Society","og_description":"Heavy smokers, typically men, run a high risk of developing lung cancer due to the carcinogenic compounds found in tobacco smoke. But while tobacco remains the main risk factor, there...","og_url":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/","og_site_name":"365 CPS Resource Hub","article_published_time":"2021-10-05T04:00:27+00:00","article_modified_time":"2023-01-31T02:44:37+00:00","og_image":[{"width":2560,"height":1707,"url":"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg","type":"image\/jpeg"}],"author":"Lim","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Lim","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#article","isPartOf":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/"},"author":{"name":"Lim","@id":"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/person\/6afe96e22e1780f4859a3cab24192bd3"},"headline":"Personalised Treatment to Fight Lung Cancer","datePublished":"2021-10-05T04:00:27+00:00","dateModified":"2023-01-31T02:44:37+00:00","mainEntityOfPage":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/"},"wordCount":486,"publisher":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/#organization"},"image":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg","keywords":["Cancer","Cancer Treatment"],"articleSection":["Blogs","Cancer Education","Cancer Info"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/","url":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/","name":"Personalised Treatment to Fight Lung Cancer | 365 Cancer Prevention Society","isPartOf":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/#website"},"primaryImageOfPage":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#primaryimage"},"image":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg","datePublished":"2021-10-05T04:00:27+00:00","dateModified":"2023-01-31T02:44:37+00:00","breadcrumb":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#primaryimage","url":"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg","contentUrl":"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/12\/Lung-Image-scaled-1-1.jpg","width":2560,"height":1707},{"@type":"BreadcrumbList","@id":"https:\/\/365cps.org.sg\/resourcehub\/personalised-treatment-to-fight-lung-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Resources","item":"https:\/\/365cps.org.sg\/resourcehub\/"},{"@type":"ListItem","position":2,"name":"Cancer Education","item":"https:\/\/365cps.org.sg\/resourcehub\/category\/education\/"},{"@type":"ListItem","position":3,"name":"Personalised Treatment to Fight Lung Cancer"}]},{"@type":"WebSite","@id":"https:\/\/365cps.org.sg\/resourcehub\/#website","url":"https:\/\/365cps.org.sg\/resourcehub\/","name":"365 CPS Resource Hub","description":"Your ultimate cancer resource","publisher":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/365cps.org.sg\/resourcehub\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/365cps.org.sg\/resourcehub\/#organization","name":"365 CPS Resource Hub","url":"https:\/\/365cps.org.sg\/resourcehub\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/logo\/image\/","url":"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/10\/365CPS-Logo-Retina.webp","contentUrl":"https:\/\/365cps.org.sg\/resourcehub\/wp-content\/uploads\/2022\/10\/365CPS-Logo-Retina.webp","width":240,"height":175,"caption":"365 CPS Resource Hub"},"image":{"@id":"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/person\/6afe96e22e1780f4859a3cab24192bd3","name":"Lim","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/365cps.org.sg\/resourcehub\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/cf6824ffefdf977dbbdf99efe33156c5dd8c50b6dd7e48e456248983f497d62c?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/cf6824ffefdf977dbbdf99efe33156c5dd8c50b6dd7e48e456248983f497d62c?s=96&d=mm&r=g","caption":"Lim"},"url":"https:\/\/365cps.org.sg\/resourcehub\/author\/yunqianlim\/"}]}},"_links":{"self":[{"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/posts\/1893","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/comments?post=1893"}],"version-history":[{"count":2,"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/posts\/1893\/revisions"}],"predecessor-version":[{"id":1944,"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/posts\/1893\/revisions\/1944"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/media\/1894"}],"wp:attachment":[{"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/media?parent=1893"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/categories?post=1893"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/365cps.org.sg\/resourcehub\/wp-json\/wp\/v2\/tags?post=1893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}